Increased Risk of Mouth Ulcers Linked to Poor Mental Health

*Updated May 2025

Research shows a strong connection between oral health and mental well-being. Stress, anxiety, depression, and loneliness can contribute to poor oral health, including the development of painful mouth ulcers.

This study from the National Library of Medicine highlights a causal link between psychological traits and an increased risk of mouth ulcers. In this article, we explore the causes of mouth ulcers and how prioritizing your mental health may help reduce your risk.

What is a mouth ulcer?

Mouth ulcers are sores that can form on your lips, gums, inner cheeks, or roof of your mouth. Sometimes called canker sores, these lesions in the mouth can be very painful, even though they’re usually not harmful to your health. The sores are often red or yellow and will go away on their own with time.

However, if you experience chronic mouth ulcers, it’s important to chat with your dentist as it could indicate a more serious health condition such as bleeding disorders, immune disorders, cancer of the mouth, and more.

What causes mouth ulcers?

Mouth ulcers can develop from various factors, including oral tissue injuries, accidental bites to the tongue or cheek, vitamin deficiencies, frequent consumption of acidic foods, infections, and abrasive toothpaste.

In addition to physical causes, these painful sores can also be triggered by stress, hormonal changes, sleep deprivation, and anxiety.

How mental is connected to mouth ulcers

Stress and anxiety have been linked to a higher likelihood of developing mouth ulcers. A study from Frontiers in Genetics suggests that stress is linked to disrupting immune system components, which leads to an overall imbalance in hormones and chemicals in the body. This imbalance is often associated with the development of mouth ulcers.

In addition to biological factors, poor mental health has been linked to an increased risk of poor oral health habits. People struggling with mental health disorders are less likely to brush their teeth, floss regularly, and go to dental check-ups.

As the connection between mental and oral health becomes clearer, there is a push for dentists and doctors to collaborate to ensure the best care for their patients. Mental health, in particular, plays a significant role in overall oral health, influencing everything from hygiene habits to the risk of certain conditions.

Recognize the mind and mouth connection

Prioritizing your mental health, managing stress, and finding healthy ways to cope with anxiety can help lower your risk of developing painful mouth ulcers—as well as other dental and medical issues. If you're struggling, seeking support from a medical professional can make a meaningful difference.